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LncRNA NONMMUT104330.1-miR-709-DDX58 axis mediates enoxaparin sodium bone cement to regulate M2 polarization of macrophages and play an anti-inflammatory immunomodulatory role

ABSTRACT: PMMA bone cement is biologically inert and exhibits poor biological activity. Following implantation, it generates bone cement particles, which can easily induce tissue inflammation around the implant . Compared with PMMA bone cement, ES-PMMA bone cement had anti-inflammatory effect by inducing M2 polarization of macrophages. RNA sequencing was used to explore the underlying molecular mechanisms.

ORGANISM(S): Mus musculus

PROVIDER: GSE279658 | GEO | 2024/10/24

REPOSITORIES: GEO

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