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Effect of PHRF1 depletion on gene expression in HeLa cells

ABSTRACT: The goal of this study was to understand how PHRF1 regulates gene expression in HeLa cells. By conducting RNA sequencing of 3 WT and 3 KO (PHRF1 knockout) samples, we found that DNA damage response pathways were upregulated and splicing-related pathways were downregulated in KO cells versus WT cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE281703 | GEO | 2024/11/18

REPOSITORIES: GEO

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