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Improved statistical analysis of budding yeast TAG microarrays

ABSTRACT: Yeast knockout collection TAG microarrays are an emergent platform for rapid, genome-wide functional characterization of yeast genes. We describe a method for analyzing two-color array data to efficiently represent differential knockout strain representation across two experimental conditions. Using a fully defined spike-in pool, we show that the sensitivity and specificity of this method exceed typical current approaches. Keywords: Saccharomyces cerevisiae, yeast, self_vs_self, spike-in pools

ORGANISM(S): Saccharomyces cerevisiae

PROVIDER: GSE2832 | GEO | 2005/09/02

SECONDARY ACCESSION(S): PRJNA92461

REPOSITORIES: GEO

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