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Effects of CYTOR Knockdown via CRISPRi on K562 cells

ABSTRACT: The long noncoding RNA CYTOR has been linked to poor prognosis of cancer, this includes chemo- and radioresistance. Knowing the mechanisms of CYTOR can benefit current cancer therapeuitics. To examine the mechanisms of CYTOR on K562, we performed CRISPRi to knock it down. RNA sequencing were then performed on these knocked down and wild type cells. This is followed by differential gene expression analysis to determine genes and lncRNAs that are differentially regulated when CYTOR is silenced.

ORGANISM(S): Homo sapiens

PROVIDER: GSE285084 | GEO | 2024/12/22

REPOSITORIES: GEO

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Effects of CYTOR Knockdown via CRISPRi on K562 cells

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