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Effect of short-term glucocorticoid treatment on gene expression of cultured neonatal cardiomyocytes

ABSTRACT: To investigate the direct effects of endogenous glucocorticoids on global gene expression of cardiomyocytes and to explore their potential impact on their proliferation and regenerative capacity, we performed whole-transcriptome RNA sequencing on primary neonatal murine cardiomyocytes cultured in vitro and treated with corticosterone. Corticosterone was administered over a short time frame to identify genes directly regulated by glucocorticoids.

ORGANISM(S): Mus musculus

PROVIDER: GSE286562 | GEO | 2025/01/18

REPOSITORIES: GEO

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