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Longitudinal ovarian cancer (BOB)

ABSTRACT: High-grade serous ovarian cancer presents significant challenges due to its poor prognosis and high heterogeneity, both of which complicate treatment responses. This project aims to understand intra-patient tumor evolution by investigating different sampling sites (primary and metastatic) at the time of diagnosis and during disease recurrence. A total of 183 biopsies from 50 patients were collected for this purpose, and bulk mRNA sequencing was performed. The majority of samples originated from following tissue types: omentum, ovary, and ascites.

ORGANISM(S): Homo sapiens

PROVIDER: GSE289067 | GEO | 2025/02/08

REPOSITORIES: GEO

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