Transcriptomics

Dataset Information

0

Gene Expression Patterns of Endothelial Cell Network Formation


ABSTRACT: Lamellar co-cultures of human aorta-derived smooth muscle cells (SMCs) cultured with cord-blood derived endothelial cells (ECs) are an in vitro model for tissue engineered blood vessels and in-growth of endothelial cells into cardiovascular repair devices. The ratio of endothelial cells to smooth muscle cells can control the EC pattern of growth and differentiation. Low density ECs form capillary-like networks in co-culture with SMCs whereas high density ECs become confluent across the top surface of the SMCs. To understand the molecular mechanisms that govern network formation, used microarray analysis of ECs purified from 1) networks, 2) confluent layers compared to 3) ECs in monoculture.

ORGANISM(S): Homo sapiens

PROVIDER: GSE30527 | GEO | 2017/03/01

SECONDARY ACCESSION(S): PRJNA143307

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2021-05-20 | GSE114776 | GEO
2020-10-29 | PXD018274 | Pride
2018-02-14 | GSE96962 | GEO
2016-08-04 | E-GEOD-74451 | biostudies-arrayexpress
2023-04-03 | GSE171709 | GEO
2020-10-20 | GSE159641 | GEO
2024-07-01 | GSE260844 | GEO
2021-06-29 | GSE175612 | GEO
2016-07-01 | E-MTAB-4841 | biostudies-arrayexpress
2023-12-08 | E-MTAB-12019 | biostudies-arrayexpress