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Profiling of Jurkat T cells activated with CD3, CD28 and PMA and multiple kinase inhibitors

ABSTRACT: T lymphocytes are orchestrators of adaptive immunity. Naïve T cells may differentiate into the Th1, Th2, Th17 or iTreg phenotype, depending on environmental co-stimulatory signals. In order to identify the genes and pathways involved in differentiation of Jurkat T cells towards Th1 and Th2 subtypes we performed comprehensive transcriptome analyses of Jurkat T cells stimulated with various stimuli an pathway inhibitors

ORGANISM(S): Homo sapiens

PROVIDER: GSE30674 | GEO | 2011/07/16

SECONDARY ACCESSION(S): PRJNA154699

REPOSITORIES: GEO

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