Transcriptomics

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Expression data from normal B cells and chronic lymphocytic leukemia B cells -- with/without treatment of Wnt3a


ABSTRACT: Wnt pathway is dysregulated in CLL-We characterized Wnt pathway gene expression in normal B and CLL-B cells and identified Wnt targets in normal B and CLL-B cells through this data set. In this dataset, we included normal B cells and CLL-B cells for Wnt pathway gene expression. This leads to the identification of 62 Wnt pathway components which are differnetially expressed between normal and CLl-B cells. We also included normal B cells and CLL-B cells with or without Wnt3a treatment and identified 468 and 676 Wnt regulated genes in normal and CLL B cells, respectively.

ORGANISM(S): Homo sapiens

PROVIDER: GSE31048 | GEO | 2013/08/29

SECONDARY ACCESSION(S): PRJNA144867

REPOSITORIES: GEO

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