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Expression data from mouse heart deficient of HDAC3

ABSTRACT: Gene expression changes in the heart of MCH3-KO mouse (HDAC3 f/f, Muscle Creatine Kinase-Cre) versus control WT mouse (HDAC3 f/f). Histone deacetylases (HDACs) play important roles in cardiac development and function. We show here that mice deficient of HDAC3 in heart and skeletabl muscle are relatively normal on normal chow, but develop hypertrophic cardiomyopathy and heart failure that leads to death on high-fat diet. This microarray experiment is to explore the underlying molecular mechanism.

ORGANISM(S): Mus musculus

PROVIDER: GSE31251 | GEO | 2011/09/21

SECONDARY ACCESSION(S): PRJNA146063

REPOSITORIES: GEO

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Expression data from mouse heart deficient of HDAC3

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