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Murine Myoblast C2C12 Cells: Control vs. Mybbp1a Knockdown

ABSTRACT: Transcriptional profiling of mouse myoblast cells comparing control vs. Mybbp1a knockdown. Stable clones of C2C12 cells harboring control or Mybbp1a-targeting shRNA were established and further pooled for analysis. Goal was to determine, based on the effects of Mybbp1a depletion on global gene expression, candidate downstream target genes of Mybbp1a, a putative transcriptional co-repressor.

ORGANISM(S): Mus musculus

PROVIDER: GSE31319 | GEO | 2011/08/10

SECONDARY ACCESSION(S): PRJNA146091

REPOSITORIES: GEO

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Murine Myoblast C2C12 Cells: Control vs. Mybbp1a Knockdown

Project description:Transcriptional profiling of mouse myoblast cells comparing control vs. Mybbp1a knockdown. Stable clones of C2C12 cells harboring control or Mybbp1a-targeting shRNA were established and further pooled for analysis. Goal was to determine, based on the effects of Mybbp1a depletion on global gene expression, candidate downstream target genes of Mybbp1a, a putative transcriptional co-repressor. Two-condition experiment, control vs. Mybbp1a knockdown C2C12 cells (mixed stable clones). Biological replicates: 2.

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