Genomics

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Comparative Genomic Hybridization of S. cerevisiae industrial and laboratory strains


ABSTRACT: The environmental stresses and inhibitors encounted by Saccharomyces cerevisiae strains are main limiting factors in bioethanol fermentation. Investigation of the molecular mechanisms underlying the stresses-related phenotypes diversities within and between S. cerevisiae populations could guide the construction of yeast strains with improved stresses tolerance and fermentation performances. Here, we explored the genetic characteristics of the bioethanol S. cerevisiae strains, and elucidated the genetic variations correlated with its advantaged traits (higher ethanol yield under sever conditions and better tolerance to multiple stresses compared to an S288c derived laboratory strain BYZ1). Firstly, pulse-field gel electrophoresis combined with array-comparative genomic hybridization was used to compare the genome structure of industrial strains and the laboratory strain BYZ1.

ORGANISM(S): Saccharomyces cerevisiae

PROVIDER: GSE31872 | GEO | 2011/09/15

SECONDARY ACCESSION(S): PRJNA145241

REPOSITORIES: GEO

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