Role of SIRT1 in human hepatocellular carcinoma
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ABSTRACT: To investigate the specific roles of SIRT1 in the development of hepatocellular carcinoma, we employed large-scale gene expression analysis to identify the molecular signature that may affect enabling characteristics of cancer cells. Differentially expressed genes were analyzed on the SNU-182 cells transfected with SIRT1 siRNA and recapitulated molecular signatures that related to hallmarks of cancer.
ORGANISM(S): Homo sapiens
PROVIDER: GSE32066 | GEO | 2012/03/01
SECONDARY ACCESSION(S): PRJNA147605
REPOSITORIES: GEO
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