Transcriptomics

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Real-time quantitative PCR analysis of ARF-deficient macrophages


ABSTRACT: Macrophages are a major cellular component of all inflammatory situations, generating proinflammatory cytokines such as TNF-alpha, IL-1, and IL-6 that are central to the initiation and maintenance of inflammation. To determine whether the tumor suppressor ARF plays a role in inflammatory gene expression, we used an 84-gene RT2 PCR array to examine the expression of inflammation-associated genes in WT and ARF-deficient macrophages treated with the TLR4 ligand LPS.

ORGANISM(S): Mus musculus

PROVIDER: GSE32446 | GEO | 2011/09/29

SECONDARY ACCESSION(S): PRJNA147721

REPOSITORIES: GEO

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