Oxidative burden and mitochondrial dysfunction in a mouse model of Rett syndrome
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ABSTRACT: To identify the detailed molecular causes of the mitochondrial dysfunction, oxidative burden and more vulnerable redox balance in Rett mouse hippocampus, we screened for differential gene expression in the hippocampal CA1 subfield of adult male mice. A whole mouse genome microarray was performed to assess, whether key enzymes of the mitochondrial respiratory chain or major cellular radical scavenging enzymes are affected in this MeCP2-deficient mouse model of Rett syndrome.
ORGANISM(S): Mus musculus
PROVIDER: GSE32870 | GEO | 2012/08/31
SECONDARY ACCESSION(S): PRJNA146559
REPOSITORIES: GEO
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