Transcriptomics

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Comparison of gene expression profiles in rat sarcomas and masenchymal stem cells (MSCs)


ABSTRACT: To investigate the altered patways among sarcomas and MSCs, gene expression profiles were comared among rat osteosarcoma and malignant histiocytoma (MFH) to mesenchymal stem cells (MSCs) from syngeneic origin. Several altered pathways have identified including down-regulation of Wnt, Cell adhesion, ECM interaction and up-regulation of Hedgehog, cell cycling pathways in rat sarcomas compared to MSCs.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE33170 | GEO | 2011/10/25

SECONDARY ACCESSION(S): PRJNA149235

REPOSITORIES: GEO

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