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Whole-transcript expression data for uveal melanoma

ABSTRACT: G protein alpha q and 11 are mutated in 90% of uveal melanoma and they activate the MAPK pathway. Using expression microarray analysis, we identified a unique MEK dependent transcriptional signature with genes that are involved in proliferation and tumor cell invasion.

ORGANISM(S): Homo sapiens

PROVIDER: GSE33655 | GEO | 2011/12/31

SECONDARY ACCESSION(S): PRJNA148641

REPOSITORIES: GEO

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Whole-transcript expression data for uveal melanoma

Project description:G protein alpha q and 11 are mutated in 90% of uveal melanoma and they activate the MAPK pathway. Using expression microarray analysis, we identified a unique MEK dependent transcriptional signature with genes that are involved in proliferation and tumor cell invasion. Uveal melanoma cells were profiled on Illumina Human HT-12 arrays per manufacturer's instructions

2011-12-31 | E-GEOD-33655 | biostudies-arrayexpress

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