Transcriptomics

Dataset Information

0

Dissection of human embryonic stem cells-derived endoderm progenitors by differential cell capture on antibody arrays


ABSTRACT: Heterogeneity, shortage of material, and lack of progenitor-specific cell surface markers are major obstacles to elucidating the mechanisms underlying developmental processes. Here we report a proteomic platform that alleviates these difficulties and demonstrate its effectiveness in fractionating heterogeneous cultures of early endoderm derived from human embryonic stem cells. The approach, designated cell-capture antibody array, is based on highly parallel, comparative screening of live cell populations using hundreds of antibodies directed against cell-surface antigens. The results demonstrate the potential of the cell-capture antibody array as a powerful tool for detailed dissection of heterogeneous cellular systems.

ORGANISM(S): Homo sapiens

PROVIDER: GSE34075 | GEO | 2012/12/29

SECONDARY ACCESSION(S): PRJNA150001

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2012-12-29 | E-GEOD-34075 | biostudies-arrayexpress
2018-06-04 | GSE92465 | GEO
2018-06-04 | GSE92464 | GEO
2024-07-08 | GSE271304 | GEO
| PRJNA85209 | ENA
2013-03-31 | E-GEOD-44032 | biostudies-arrayexpress
2013-11-15 | GSE50185 | GEO
2013-11-15 | E-GEOD-50185 | biostudies-arrayexpress
2022-01-24 | PXD014165 | Pride
2020-08-25 | GSE156766 | GEO