Airway smooth muscle reponse to dexamathasone at 4 and 24 hours
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ABSTRACT: Glucocorticoids, which activate glucocorticoid receptor signaling and thus modulate gene expression, are widely used to treat asthma. Glucocorticoids exert their therapeutic effects in part through modulating airway smooth muscle structure and function. However, the effects of genes that are regulated by GCs on airway function are not fully understood. Here, we used transcription profiling to characterize the effects of a potent glucocorticoid, dexamethasone, on cultured human airway smooth muscle gene expression at 4 and 24 hours.
ORGANISM(S): Homo sapiens
PROVIDER: GSE34313 | GEO | 2011/12/10
SECONDARY ACCESSION(S): PRJNA151509
REPOSITORIES: GEO
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