Male-dominant activation of rat renal organic anion transporter 1 (Oat1) and 3 (Oat3) expression by transcription factor BCL6
Ontology highlight
ABSTRACT: Organic anion transporters 1 (Oat1) and 3 (Oat3) play a critical role in transport of organic anions, including frequently prescribed drugs, across cell membranes in proximal tubules of kidneys. In rats, these transporters are known to be male-predominant and testosterone dependently expressed. The molecular mechanisms that are involved in the sex-dependent expression are unknown. Our aim was to identify genes that show a sex-dependent expression and could be involved in sex-dependent regulation of Oat1 and Oat3.
ORGANISM(S): Rattus norvegicus
PROVIDER: GSE34565 | GEO | 2012/04/18
SECONDARY ACCESSION(S): PRJNA151031
REPOSITORIES: GEO
ACCESS DATA