Transcriptomics

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Male-dominant activation of rat renal organic anion transporter 1 (Oat1) and 3 (Oat3) expression by transcription factor BCL6


ABSTRACT: Organic anion transporters 1 (Oat1) and 3 (Oat3) play a critical role in transport of organic anions, including frequently prescribed drugs, across cell membranes in proximal tubules of kidneys. In rats, these transporters are known to be male-predominant and testosterone dependently expressed. The molecular mechanisms that are involved in the sex-dependent expression are unknown. Our aim was to identify genes that show a sex-dependent expression and could be involved in sex-dependent regulation of Oat1 and Oat3.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE34565 | GEO | 2012/04/18

SECONDARY ACCESSION(S): PRJNA151031

REPOSITORIES: GEO

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