Genomics

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Estrogen-responsive Estrogen Receptor alpha binding sites in MCF-7 by ChIP-seq


ABSTRACT: Identification of Estrogen Receptor alpha (ERa) binding sites by ChIP-seq in MCF-7 breast cancer cells following an estrogen treatment. This study describes molecular effects of estradiol treatment and subsequent regulation by ER for a single gene/locus. A public ER chipseq (available in SRA as ERR011973), in addition to our own data, guided us to regulatory regions were ER was binding that were then analyzed in detail using "manual" ChIP.

ORGANISM(S): Homo sapiens

PROVIDER: GSE34759 | GEO | 2012/12/17

SECONDARY ACCESSION(S): PRJNA150381

REPOSITORIES: GEO

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