Direct reprogramming of human astrocytes into neural stem cells and neurons

ABSTRACT: Ectopic expression of the reprogramming factors OCT4, SOX2, or NANOG into human astrocytes in specific cytokine/culture conditions activated the neural stem gene program and induced generation of cells expressing neural stem/precursor markers.

ORGANISM(S): Homo sapiens

PROVIDER: GSE36145 | GEO | 2013/12/01

SECONDARY ACCESSION(S): PRJNA172206

REPOSITORIES: GEO