Genomics

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SNP-based LOH of hepatocellular carcinoma (HCC)


ABSTRACT: High frequency of loss of heterozygosity (LOH) at locus D4S2964 was found in hepatocellular carcinoma (HCC) by our previous studies and others’. The present study was designed to explore genes around the locus affected by LOH and their clinical implications. 440 SNPs located at 49 genes around D4S2964 were selected from NCBI website for the SNPs microarray fabrication. LOH of these SNPs markers in 112 cases of HCC tissues and paired adjacent liver tissues were investigated by the SNP microarray. A map of LOH of SNPs in genes around D4S2964 was constructed.

ORGANISM(S): Homo sapiens

PROVIDER: GSE36277 | GEO | 2015/02/28

SECONDARY ACCESSION(S): PRJNA153005

REPOSITORIES: GEO

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