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Distinct tumorigenic pathways within hereditary nonpolyposis colorectal cancer

ABSTRACT: Gene expression profiling has discriminated between sporadic microsatellite instable (MSI) and microsatellite stable (MSS) colorectal cancers (CRCs), whereas the expression pattern of familial colorectal cancer type X (FCCTX) and Lynch syndrome (LS) associated CRCs remain largely unknown. The purpose of this study is to use gene expression profiling of formalin-fixed paraffin-embedded (FFPE) tumor specimens from FCCTX, LS and sporadic CRC as a control to detect expression patterns and to identify signaling pathways differing between FCCTX and LS tumors.

ORGANISM(S): Homo sapiens

PROVIDER: GSE36335 | GEO | 2012/03/08

SECONDARY ACCESSION(S): PRJNA153389

REPOSITORIES: GEO

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Distinct tumorigenic pathways within hereditary nonpolyposis colorectal cancer

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