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C. elegans young adults cultured on Bacillus subtilis strain 67 vs cultured on E. coli OP50

ABSTRACT: Transcriptional profiling of C. elegans young adult worms cultured on non-pathogenic Bacillus subtilis strain 67 versus age-matched worms cultured on the control lab food E. coli OP50. The goal was to identify genes regulated in response to differences in diet, which potentially confer immunity to later exposures to pathogenic Bacillus thuringiensis DB27.

ORGANISM(S): Caenorhabditis elegans

PROVIDER: GSE36733 | GEO | 2012/03/27

SECONDARY ACCESSION(S): PRJNA156751

REPOSITORIES: GEO

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C. elegans young adults cultured on Bacillus strain 67 vs cultured on E. coli OP50

Project description:Transcriptional profiling of C. elegans young adult worms cultured on non-pathogenic Bacillus strain 67 versus versus age-matched worms cultured on the control lab food E. coli OP50. The goal was to identify genes regulated in response to differences in diet, which might confer immunity to later exposures to pathogenic Bacillus thuringiensis DB27. One-condition experiment. C. elegans young adults, cultured on : Bacillus strain 67 versus E. coli OP50. 4 biological replicates, including 2 dye-swaps.

2012-03-26 | E-GEOD-36733 | biostudies-arrayexpress

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2012-03-13 | E-GEOD-36413 | biostudies-arrayexpress

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Project description:Transcriptional profiling of P. pacificus young adult worms exposed to pathogen Serratia marcescens for 4 hours versus age-matched worms exposed to control lab food E. coli OP50. The goal was to identify genes regulated in response to pathogen. The broader goal of study was to study evolution of pathogen response by comparing this expression profile to that obtained by exposing the nematode C. elegans to the same pathogen. Other experiments which are a part of this study include expression profiling of C. elegans and P. pacificus on other pathogens including , Bacillus thuringiensis DB27, Serratia marcescens and Xenorhabdus nematophila.

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C. elegans young adults: Exposed to Bacillus thuringiensis DB27 versus exposed to E. coli OP50 : 4 hours

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P. pacificus young adults: Exposed to Serratia marcescens versus exposed to E. coli OP50 : 4 hours

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