Age-specific variation in immune response in Drosophila melanogaster has a genetic basis.
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ABSTRACT: Immunosenescence, the age-related decline in immune system function, is a general hallmark of aging. While much is known about the cellular and physiological changes that accompany immunosenescence, we know very little about the genetic influences on this phenomenon. We used microarrays to determine genome-wide expression profiles in twelve inbred D. melanogaster lines that varied in their ability to to clear an E. coli infection at one and four weeks of age.
ORGANISM(S): Drosophila melanogaster
PROVIDER: GSE37708 | GEO | 2012/05/03
SECONDARY ACCESSION(S): PRJNA163089
REPOSITORIES: GEO
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