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Notch1 activation and TGF-beta stimulation in transformed human esophageal cells

ABSTRACT: Transformed human esophageal keratinocyte cell line EPC2-T (EPC2-hTERT-EGFR-cyclin D1-p53R175H) cells were stimulated with or without 2.5 ng/ml recombinant human TGF-beta1 for 10 days. The above cells were subjected to treatment for 10 days with or without 0.5 µg/ml doxycycline (DOX) to activate tetracycline-inducible (tet-on) ICN1, an active form of Notch1.

ORGANISM(S): Homo sapiens

PROVIDER: GSE37994 | GEO | 2014/12/31

SECONDARY ACCESSION(S): PRJNA167089

REPOSITORIES: GEO

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