An overlapping protein-coding region in Influenza A Virus Segment 3 modulates the host response
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ABSTRACT: Segment 3 of influenza A virus contains a second open reading frame accessed via robosomal frameshifting. The frameshift product, PA-Z, comprises the endonuclease domain of viral PA protein with C-terminal demain encoded by the X-ORF and functions to repress cellular gene expression. PA-X also modulates IAV virulence in a mouse infection model.
ORGANISM(S): Mus musculus
PROVIDER: GSE38112 | GEO | 2012/07/12
SECONDARY ACCESSION(S): PRJNA167288
REPOSITORIES: GEO
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