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MiRNA Expression in AMuLV Cell Lines upon STI571 Treatment

ABSTRACT: We conducted a screen for miRNAs that have a change in expression upon STI571 treatment of AMuLV pro-B cells. We used AMuLV pro-B cells as a model system to identify miRNAs important at the pro-B to pre-B transition in developing B cells in vivo. Previous groups have shown that miRNAs are necessary for the pro-B to pre-B transition. We hypothesize that specific miRNAs induced upon STI571 treatment, regulate important developmental programs and pathways to the pre-B stage of B cell development.

ORGANISM(S): synthetic construct Mus musculus

PROVIDER: GSE38331 | GEO | 2012/05/31

SECONDARY ACCESSION(S): PRJNA167736

REPOSITORIES: GEO

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miRNA Expression in AMuLV Cell Lines upon STI571 Treatment

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