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Gene expression of three hepatocellular carcinoma cell lines with different organ-tropism.

ABSTRACT: In this study we investigated the gene expression profiling in three HCC cell lines with different organ-tropism.The parent cell line has low metastasis ability in nude mice model. Subclone 1 has higher metastasis ability specific to lung, and subclone 2 has dual metastasis ability to lung and celiac lymph node. We aimed to explore differentially expressed genes involved in process of HCC metastasis and organ-specific metastasis, and identify their biological functions.

ORGANISM(S): Homo sapiens

PROVIDER: GSE38945 | GEO | 2014/06/30

SECONDARY ACCESSION(S): PRJNA169359

REPOSITORIES: GEO

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Gene expression of three hepatocellular carcinoma cell lines with different organ-tropism.

Project description:In this study we investigated the gene expression profiling in three HCC cell lines with different organ-tropism.The parent cell line has low metastasis ability in nude mice model. Subclone 1 has higher metastasis ability specific to lung, and subclone 2 has dual metastasis ability to lung and celiac lymph node. We aimed to explore differentially expressed genes involved in process of HCC metastasis and organ-specific metastasis, and identify their biological functions. Examination of different gene expression among the 3 cell types.

2014-06-30 | E-GEOD-38945 | biostudies-arrayexpress

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comparison of mRNA expression among rat hepatoma cell lines with different metastatic ability

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comparison of mRNA expression among rat hepatoma cell lines with different metastatic ability

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Organ-specific tropism and adaptation after metastasis of ER+ breast cancers

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