Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA sequencing in fly heads to examine the effect of spermidine feeding on transcription in the ageing fly brain.

ABSTRACT: mRNA sequencing was used to identify genome wide transcriptional changes occuring in fly heads in response to spermidine feeding. This study shed light on the molecular mechanisms through wich spermidine can protect against age-dependent memory impairment.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE38998 | GEO | 2013/09/01

SECONDARY ACCESSION(S): PRJNA169561

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

RNA sequencing in fly heads to examine the effect of spermidine feeding on transcription in the ageing fly brain.

Project description:mRNA sequencing was used to identify genome wide transcriptional changes occuring in fly heads in response to spermidine feeding. This study shed light on the molecular mechanisms through wich spermidine can protect against age-dependent memory impairment. mRNA profiles from 3 and 10 day old Drosophila melanogaster heads were generated in duplicate by deep sequencing using Illumina GAIIx. mRNA profiles from flies that were fed food with 5mM spermidine were compared to profiles from flies that had no spermidine in thier food.

2013-09-01 | E-GEOD-38998 | biostudies-arrayexpress

CLK targets from fly heads

Project description:CLK targets from fly heads using the TIM-GAL4; UAS-CLKGR line Keywords: CLK TARGETS

2007-07-09 | GSE7646 | GEO

Ribosome footprinting of fly heads

Project description:We applied ribosomal footprinting experiment followed by RNA-seq in order to detect circular RNA associated with ribosomes in fly heads.

2017-03-24 | GSE79626 | GEO

Transcription profiling of wild type fly heads (CantonS) and eye-less fly heads (sine occulis)

Project description:To identify the eye-enriched genes by comparing the mRNA expression profiles from wild type fly heads (CantonS) and eye-less fly heads (sine occulis).

2012-05-17 | E-MEXP-49 | biostudies-arrayexpress

Total RNA from different species fly heads

Project description:Total RNA seq from different species fly heads at different temperatures

2019-12-03 | GSE124142 | GEO

Diet and CLK-dependent expression changes in fly heads

Project description:This study aims to elucidate how the core circadian transcription factor, CLOCK (Clk), mediates diet-dependent transcriptional changes in fly heads. In particular, we sought to identify how CLK influences gene-level expression changes in fly heads from flies that had been reared on either a high nutrient or low nutrient (dietary restriction) diet.

2020-10-02 | GSE158905 | GEO

Transcriptome analysis of w1118 and miR-210 mutant adult fly heads

Project description:We report the genome-wide RNA profiling of adult fly heads upon miR-210 mutation

2020-10-14 | GSE146335 | GEO

Spermidine Yeast Aging Array

Project description:Administration of spermidine, a natural polyamine whose intracellular concentration declines during human ageing, markedly extends the lifespan of various model organisms including yeast, flies and worms. In ageing yeast, spermidine treatment triggeres epigenetic deacetylation of histone H3 through inhibition of histone acetyltransferases (HAT), leading to induction of autophagy and thereby suppressing oxidative stress and necrosis. In order to further characterize the effects by spermidine supplementation of aging yeast cultures and to understand how global histone deacetylation affects gene transcription during aging, Affymetrix-based microarray analyses of three day old as well as ten day old cultures with and without administration of spermidine was performed.

2012-01-04 | E-MTAB-912 | biostudies-arrayexpress