Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Transcription profiling of wild type fly heads (CantonS) and eye-less fly heads (sine occulis)


ABSTRACT: To identify the eye-enriched genes by comparing the mRNA expression profiles from wild type fly heads (CantonS) and eye-less fly heads (sine occulis).

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Hong-Shen Li 

PROVIDER: E-MEXP-49 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

A lysosomal tetraspanin associated with retinal degeneration identified via a genome-wide screen.

Xu Hong H   Lee Seung-Jae SJ   Suzuki Emiko E   Dugan Katherine D KD   Stoddard Alexander A   Li Hong-Sheng HS   Chodosh Lewis A LA   Montell Craig C  

The EMBO journal 20040212 4


The Drosophila visual system has provided a model to study phototransduction and retinal degeneration. To identify new candidate proteins that contribute to these processes, we conducted a genome-wide screen for genes expressed predominately in the eye, using DNA microarrays. This screen appeared to be comprehensive as it led to the identification of all 22 eye-enriched genes previously shown to function in phototransduction or implicated in retinal degeneration. In addition, we identified 93 ey  ...[more]

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