Transcriptomics

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CXCL12 and IGF1 select for cancer cell populations with enhanced bone metastasis ability


ABSTRACT: CXCL12 and IGF1 confer on cancer cells survival advantage. Src potentiates cancer cells' reponse to CXCL12 and IGF1 by strengthening AKT activation. Long-term incubation of CXCL12 and IGF1 select for cancer cells with enhanced Src activity and bone metastasis potential.

ORGANISM(S): Homo sapiens

PROVIDER: GSE39102 | GEO | 2012/12/10

SECONDARY ACCESSION(S): PRJNA170054

REPOSITORIES: GEO

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