Genomics

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Array-CGH on single blastomeres from day-4 human preimplantation fresh and frozen embryos


ABSTRACT: In total, 240 single blastomeres from nine top-quality day-4 embryos frozen at day 3 of development and four fresh top-quality day-4 embryos that had one-cell biopsy on day 3 for preimplantation genetic diagnosis (PGD) were collected. Blastomeres' DNA was amplified using SurePlex DNA Amplification System (BlueGnome, Cambridge, UK) . Array-CGH was carried out using 24Sure Cytochip microarrays following the standard protocol (BlueGnome, www.cytochip.com).

ORGANISM(S): Homo sapiens

PROVIDER: GSE39518 | GEO | 2013/04/05

SECONDARY ACCESSION(S): PRJNA171590

REPOSITORIES: GEO

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