Genomics

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Genome-wide maps of Six2 and b-catenin in mesenchymal nephron progenitors


ABSTRACT: Self-renewing undifferentiated nephron progenitors express Six2, a transcription factor that is required for their maintenance as undifferentiated progenitors. Differentiation of nephron progenitors is triggered by Wnt/b-catenin signaling. In order to understand how Six2 and Wnt signaling counteract each other, we performed ChIP-seq of Six2 and b-catenin in mesenchymal nephron progenitor cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE39837 | GEO | 2012/09/11

SECONDARY ACCESSION(S): PRJNA172117

REPOSITORIES: GEO

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