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Gene expression analysis of human microRNA-150 expression in PL21 and HL60 cells

ABSTRACT: Analysis of gene expression changes associated with lentiviral vector mediated expression of pre-microRNA-150 expression in the AML cell lines PL21 and HL60 cells. To identify genes, direct putative miRNA-150 targets, biological and molecular functions and pathways that distinguish cells that express miR-150 from those that do not.

ORGANISM(S): Homo sapiens

PROVIDER: GSE40147 | GEO | 2013/01/15

SECONDARY ACCESSION(S): PRJNA172926

REPOSITORIES: GEO

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Gene expression analysis of human microRNA-150 expression in PL21 and HL60 cells

Project description:Analysis of gene expression changes associated with lentiviral vector mediated expression of pre-microRNA-150 expression in the AML cell lines PL21 and HL60 cells. To identify genes, direct putative miRNA-150 targets, biological and molecular functions and pathways that distinguish cells that express miR-150 from those that do not. Total RNA isolated from HL60 or PL21 cells transduced with pre-microRNA-150 or empty vector control and assayed by gene expresssion analysis 20 days post transduction. Two replicates were performed for each condition (miR-150 and control) in each of two cell lines (HL60 and PL21).

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