Transcriptomics

Dataset Information

0

Differentially expressed genes during disuse atrophy.


ABSTRACT: To identify atrophy genes directly targeted by Bcl-3 transactivator at a genome wide level, we performed whole transcript expression array and ChIP-seq for muscles from weight bearing or 5-day hind limb unloaded mice. Genes that showed increased expression with unloading and a Bcl-3 peak in the promoter (from ChIP-seq data) were considered as Bcl-3 direct targets during disuse atrophy. Using ChIP array, we identified 241 direct targets for Bcl-3. Our data describe Bcl-3 as a global regulator both of the proteolysis and the change in energy metabolism that are essential components of muscle atrophy due to disuse.

ORGANISM(S): Mus musculus

PROVIDER: GSE40578 | GEO | 2012/11/10

SECONDARY ACCESSION(S): PRJNA174343

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2012-11-10 | E-GEOD-40578 | biostudies-arrayexpress
2011-01-10 | E-GEOD-23497 | biostudies-arrayexpress
2011-01-10 | GSE23497 | GEO
2024-01-23 | GSE248869 | GEO
2023-01-02 | GSE220641 | GEO
2021-09-01 | GSE167462 | GEO
2007-08-28 | GSE8872 | GEO
2021-08-12 | GSE158987 | GEO
2007-08-28 | E-GEOD-8872 | biostudies-arrayexpress
2022-09-27 | GSE211204 | GEO