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Epigenetic analysis of men with low birth weight following a control and high-fat overfeeding diet

ABSTRACT: Genome-wide DNA methylation profiling of young men born with low birth weight following a control and high-fat overfeeding diet using Illumina's Infinium 27k Human DNA methylation Beadchip v. 1.2. DNA methylation profiles were obtained for 27,578 CpG sites in human skeletal muscle.

ORGANISM(S): Homo sapiens

PROVIDER: GSE40798 | GEO | 2014/01/01

SECONDARY ACCESSION(S): PRJNA175002

REPOSITORIES: GEO

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Epigenetic analysis of men with low birth weight following a control and high-fat overfeeding diet

Project description:Genome-wide DNA methylation profiling of young men born with low birth weight following a control and high-fat overfeeding diet using Illumina's Infinium 27k Human DNA methylation Beadchip v. 1.2. DNA methylation profiles were obtained for 27,578 CpG sites in human skeletal muscle. Randomized cross-over desgin, where all subjects receieved both treatments (control and high-fat overfeeding diet). Biopsies were obtained from 17 different individuals amounting to 16 samples following the control diet and 15 samples following the high-fat overfeeding diet (paired n=14). Bisulphite converted DNA from the 31 samples were hybridised to the Illumina Infinium 27k Human Methylation Beadchip.

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