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Expression analysis of HepG2, HepG2-slug and HepG2-slug on Matrigel

ABSTRACT: Investigation of whole genome gene expression level changes in hepatocellular carcinoma cell line hepG2 in regular culture, hepG2-slug in regular culture and hepG2-slug on Matrigel. Whole genome gene expression level changes have been compared in hepatocellular carcinoma cell line hepG2 in regular culture, hepG2-slug in regular culture and hepG2-slug on Matrigel.

ORGANISM(S): Homo sapiens

PROVIDER: GSE41026 | GEO | 2012/09/21

SECONDARY ACCESSION(S): PRJNA175581

REPOSITORIES: GEO

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Expression analysis of HepG2, HepG2-slug and HepG2-slug on Matrigel

Project description:Investigation of whole genome gene expression level changes in hepatocellular carcinoma cell line hepG2 in regular culture, hepG2-slug in regular culture and hepG2-slug on Matrigel. Whole genome gene expression level changes have been compared in hepatocellular carcinoma cell line hepG2 in regular culture, hepG2-slug in regular culture and hepG2-slug on Matrigel. Roche NimbleGen micro-array analysis was employed to assess global genome expression in HepG2 in regular culture, HepG2-slug in regular culture and HepG2-slug on Matrigel. The results demonstrated that the up-regulated genes and the down-regulated genes increased significantly when HepG2-slug cells with VM forming ablity were cultured on Matrigel and formed VM.

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Homo sapiens

Project description:Expression analysis of HepG2, HepG2-slug and HepG2-slug on Matrigel

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Chip-chip from HepG2 cells and HepG2 cells with slug overexpression

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