Expression profiles of zebrafish transgenic line Tg(fabp10a:def)-I

ABSTRACT: We previously reported that Def (Digestive-organ expansion factor) was a pan-endodermal enriched factor that is essential for the growth of digestive organs in zebrafish using a def mutant line hi429 as model (Chen et al., 2005). To further elucidate Def function, we generated a Def over-expressed zebrafish line, namely Tg (fabp10a:def)-I, in which def expression was under the control of a liver-specific promoter fabp10a. We used microarrays to detail the global programme of gene expression in Tg (fabp10a:def)-I transgenic line compared with wild type zebrafish control, and identified distinct classes of differently regulated genes in Tg (fabp10a:def)-I line.

ORGANISM(S): Danio rerio

PROVIDER: GSE41059 | GEO | 2013/02/28

SECONDARY ACCESSION(S): PRJNA175641

REPOSITORIES: GEO