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Role of REST in the pathogenesis of uterine fibroids

ABSTRACT: The loss of REST in uterine fibroids promotes aberrant gene expression and enables mTOR pathway activation

ORGANISM(S): Homo sapiens

PROVIDER: GSE41386 | GEO | 2012/10/06

SECONDARY ACCESSION(S): PRJNA176725

REPOSITORIES: GEO

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Role of REST in the pathogenesis of uterine fibroids

Project description:The loss of REST in uterine fibroids promotes aberrant gene expression and enables mTOR pathway activation We used siRNA to knockdown REST/ NRSF in cultured primary myometrial smooth muscle cells (SMCs) and global gene expression was analyzed using microarrays.

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