Molecular Analysis of antigen-specific B cell responses
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ABSTRACT: In order to better understand the factors that regulate B cell differentiation upon exposure to antigen, we compares global gene expression profiles from naive B cells with antigen-specific plasma, germinal center, and memory B cells after immunization with the T-dependent antigen, NP-CGG. The memory B cell-enriched transcripts were then compared with memory T cell-enriched and hematopoietic stem cell-enriched transcripts in order to generate a transcriptional profile of self-renewal within the hematopoietic system. Keywords: Cell Type Comparison
ORGANISM(S): Mus musculus
PROVIDER: GSE4142 | GEO | 2006/02/02
SECONDARY ACCESSION(S): PRJNA94991
REPOSITORIES: GEO
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