A global transcriptome analysis of keratinocytes upon suppression of endogenous microRNA-31
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ABSTRACT: MiR-31 is one of the most highly overexpressed miRNAs in psoriasis skin; however, its biological role in the disease has not been studied. Here we show that miR-31 is markedly overexpressed in psoriasis keratinocytes. To study the biological role of miR-31 in keratinocytes, we transfected miR-31 hairpin inhibitor (anti-miR-31) into primary human keratinocytes to inhibit endogenous miR-31. We performed a global transcriptome analysis of keratinocytes upon suppression of endogenous miR-31 using Affymetrix arrays.
ORGANISM(S): Homo sapiens
PROVIDER: GSE41905 | GEO | 2012/10/30
SECONDARY ACCESSION(S): PRJNA178462
REPOSITORIES: GEO
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