Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

COHCAP HCT116 Mutant Comparison [expression]

ABSTRACT: Genome-wide expression and methylation differences are compared for a normal HCT116 cell line and a derived mutant with altered DNA methylation patterns.

ORGANISM(S): Homo sapiens

PROVIDER: GSE42307 | GEO | 2013/06/08

SECONDARY ACCESSION(S): PRJNA181148

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

COHCAP HCT116 Mutant Comparison [methylation]

Project description:Genome-wide expression and methylation differences are compared for a normal HCT116 cell line and a derived mutant with altered DNA methylation patterns.

2013-06-08 | GSE42308 | GEO

COHCAP HCT116 Mutant Comparison [methylation]

Project description:Genome-wide expression and methylation differences are compared for a normal HCT116 cell line and a derived mutant with altered DNA methylation patterns. The data compares the effect of a gene mutation on genome-wide expression (and methylation). This data is being published as a technical test of utility for a novel integrative genomic algorithm (COHCAP) Keywords: parental, mutant

2013-06-08 | E-GEOD-42308 | biostudies-arrayexpress

COHCAP HCT116 Mutant Comparison [expression]

2013-06-08 | E-GEOD-42307 | biostudies-arrayexpress

COHCAP MIRA / 450k Comparison [MIRA]

Project description:Compare a single sample run with two different technologies: Illumina 450k methylation array and MIRA on NimbleGen

2013-06-08 | GSE42734 | GEO

COHCAP MIRA / 450k Comparison [450k]

Project description:Compare a single sample run with two different technologies: Illumina 450k methylation array and MIRA on NimbleGen

2013-06-08 | GSE42707 | GEO

RNA-seq of HCT116 and HCT116-DKO colon cancer cell lines

Project description:RNA-seq was performed on parental HCT116 colon cancer cell line and on HCT116 DKO (double knock-out) cell line, which contains genetic knockouts of both DNA methyltransferases DNMT1 (-/-) and DNMT3b (-/-).

2019-06-07 | GSE82338 | GEO

Genome-wide total RNA and MBD-sequencing in HCT116 and DKO cells as a global re-expression model [RNA-Seq]

Project description:Genome-wide view of the interplay between methylation and RNA expression in this colorectal cancer model was obtained. RNA-sequencing of HCT116 cell line, the DNMT1 and DNMT3B double knock-out HCT116 cell line (DKO), and 7 additional colorectal cell lines.

2013-10-01 | E-GEOD-45332 | biostudies-arrayexpress

(CTA) expression after exposure to 5-aza-2'-deoxycytidine in HCT116 cells

Project description:The expression of CTAs is normally restricted to gametogenic tissue but is often reactivated in the tumorigenic setting. This tumorigenic reactivation is thought to be due to global demethylation events during tumorigenesis. To test this, we employed an affymetrix microarray in the hypermethylated colorectal carcinoma tumor-derived cell line, HCT116, following 5-aza-2'-deoxycytidine treatment. We used microarray analysis to uncover genes whose expression is modulated by DNA methylation in the colorectal carcinoma tumor derived cell line, HCT116. HCT116 cells were exposed to 5-aza-2'-deoxycytidine for 72 hours. Total RNA was isolated and hybridized on to Affymetrix microarrays.

2016-05-31 | E-GEOD-79041 | biostudies-arrayexpress