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Genomewide analysis of U1C-dependent alternative splicing

ABSTRACT: To investigate whether U1C plays a role in splicing regulation in human system, we performed siRNA-mediated knockdown of U1C in HeLa cells and analyzed alternative splicing patterns by high-throughput RNA sequencing (RNAseq)

ORGANISM(S): Homo sapiens

PROVIDER: GSE42485 | GEO | 2013/09/30

SECONDARY ACCESSION(S): PRJNA182113

REPOSITORIES: GEO

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Genomewide analysis of U1C-dependent alternative splicing

Project description:To investigate whether U1C plays a role in splicing regulation in human system, we performed siRNA-mediated knockdown of U1C in HeLa cells and analyzed alternative splicing patterns by high-throughput RNA sequencing (RNAseq) RNAseq performed with poly(A)+ selected total RNA from U1C-knockdown and control-treated HeLa cells

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