Transcriptomics

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Genome-wide profiling of long non-coding RNAs in Arabidopsis


ABSTRACT: We developed a stringent selection pipeline for lncRNA identification, combining high-throughput RNA sequencing and computational approaches. Using this pipeline, we annotated 1,353 lncRNAs in Arabidopsis thaliana. We further found that one fifth of the lncRNAs were associated with Polycomb repressive complex 2 (PRC2). Some PRC2-associated lncRNAs could repress the transcription of their neighboring genes through mediating histone H3 lysine 27 trimethylation.

ORGANISM(S): Arabidopsis thaliana

PROVIDER: GSE42695 | GEO | 2015/11/28

SECONDARY ACCESSION(S): PRJNA182746

REPOSITORIES: GEO

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