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Gene expression microarray analysis on the medial prefrontal cortex of Schnurri-2 knockout and wild-type control mice

ABSTRACT: Schnurri-2 (Shn-2), an NF-kappa B site-binding protein, tightly binds to the enhancers of major histocompatibility complex (MHC) class I genes and inflammatory cytokines, which have been shown to harbor common variant single nucleotide polymorphisms associated with schizophrenia. Shn-2 knockout mice show behavioral abnormalities that strongly resemble those of schizophrenics. We performed gene expression microarray analysis of prefrontal cortices from Shn-2 knockout and wild-type control mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE42775 | GEO | 2013/08/13

SECONDARY ACCESSION(S): PRJNA183118

REPOSITORIES: GEO

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Gene expression microarray analysis on the medial prefrontal cortex of Schnurri-2 knockout and wild-type control mice

Project description:Schnurri-2 (Shn-2), an NF-kappa B site-binding protein, tightly binds to the enhancers of major histocompatibility complex (MHC) class I genes and inflammatory cytokines, which have been shown to harbor common variant single nucleotide polymorphisms associated with schizophrenia. Shn-2 knockout mice show behavioral abnormalities that strongly resemble those of schizophrenics. We performed gene expression microarray analysis of prefrontal cortices from Shn-2 knockout and wild-type control mice. Prefrontal cortex RNA isolated from six Shn-2 knockout and six control wild-type mice were compared.

2013-08-13 | E-GEOD-42775 | biostudies-arrayexpress

Gene expression microarray analysis on hippocampus of Schnurri-2 knockout and wild-type control mice

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Gene expression microarray analysis on hippocampus of Schnurri-2 knockout and wild-type control mice

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Genome-wide analysis of Smad and Schnurri transcription factors in C. elegans

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Gene expression microarray analysis on the medial prefrontal cortex and dentate gyrus of Schnurri-2 knockout and wild-type control mice

Project description:This SuperSeries is composed of the SubSeries listed below.

2013-08-13 | GSE42778 | GEO

Gene expression microarray analysis on the medial prefrontal cortex and dentate gyrus of Schnurri-2 knockout and wild-type control mice

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

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