Transcriptomics

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Expression data from TNF-stimulated mouse glomeruli


ABSTRACT: The specific contribution of the two TNF-receptors Tnfr1 and Tnfr2 to TNF-induced inflammation in the glomerulus is unknown. In mice, TNF exposure induces glomerular expression of inflammatory mediators like adhesion molecules and chemokines in vivo, and glomerular accumulation of leukocytes. To examine Tnfr-specific inflammatory responses in intrinsic glomerular cells but not infiltrating leukocytes we performed microarray gene expression profiling on intact glomeruli isolated from wild-type and Tnfr-deficient mice following TNF exposure in vitro.

ORGANISM(S): Mus musculus

PROVIDER: GSE43928 | GEO | 2013/09/11

SECONDARY ACCESSION(S): PRJNA188227

REPOSITORIES: GEO

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