Transcriptomics

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Genome-wide analysis reveals CLF-regulated transcripts in Arabidopsis


ABSTRACT: CURLY LEAF (CLF), the major histone methyltransferase of Polycomb Repressive Complex 2 (PRC2), modifies trimethylation of histone H3 lysine 27 (H3K27me3) and mediates dynamical chromatin repression in Arabidopsis. Here we profiled Arabidopsis transcriptomes obtained from roots, leaves, flowers and siliques of Col-0 and clf-28 plants using RNA-seq. Our analysis uncovered 3835 transcription units were up-regulated in clf-28. Compared with H3K27me3 ChIP-CHIP data, we found at least 42% of them were associated with H3K27me3.

ORGANISM(S): Arabidopsis thaliana

PROVIDER: GSE43983 | GEO | 2015/02/01

SECONDARY ACCESSION(S): PRJNA188296

REPOSITORIES: GEO

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