Transcriptomics

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Expression data from undifferentiated and differentiated mouse female ES cells PGK12.1


ABSTRACT: Affymetrix 430 2.0 mouse arrays were used for expression analyses in undifferentiated and differentiated PGK12.1 ES cells. We found that the X:autosome expression ratios calculated from the mean expression values of X-linked and autosomal genes from microarrays was ~1.4 in undifferentiated female ES cells and then decreased to 1.2 in PGK12.1 cells after 15-day embryoid body differentiation. Thus, a substantial level of X upregulation is already evident in these ES cells prior to differentiation. Our findings based on Affymetrix expression arrays are consistent with microarray analysis from other labs and our RNA-seq analysis of mouse female PGK12.1 ES cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE44251 | GEO | 2013/02/15

SECONDARY ACCESSION(S): PRJNA189295

REPOSITORIES: GEO

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